Creatine is a phosphocreatine system modulator that potentially helps mitigate neuronal energy metabolism dysfunction in Visual Snow Syndrome by enhancing mitochondrial energy production and cellular phosphocreatine reserves. Its mechanism likely involves improving neuronal metabolic efficiency, potentially reducing cortical hyperexcitability and stabilizing neuronal membrane potential through enhanced energy buffering. By supporting neuroenergetic processes, creatine may help ameliorate the neurological dysregulation associated with Visual Snow Syndrome.