Vitamin B2 (riboflavin) may potentially mitigate Visual Snow Syndrome symptoms through its role in mitochondrial energy metabolism and neurotransmitter synthesis, potentially improving neuronal function and reducing cortical hyperexcitability. Its mechanism involves supporting flavin adenine dinucleotide (FAD) and flavin mononucleotide (FMN) cofactor production, which are critical for neurological processes and may help modulate aberrant cortical signaling associated with the syndrome.