Lucent Patient

snris

Treatment for Depersonalization-derealization disorder (DPDR)

SNRIs (Serotonin-Norepinephrine Reuptake Inhibitors) modulate neurotransmitter activity by blocking the reuptake of serotonin and norepinephrine, potentially alleviating DPDR symptoms through enhanced synaptic neurotransmitter availability. By increasing neural signaling in key brain regions associated with emotional processing and perception, SNRIs may help reduce the dissociative experiences characteristic of DPDR and improve overall cognitive-emotional regulation.

2.8

AVERAGE EFFICACY

CASE STUDIES

REDDIT COMMENTS

REPORTED SIDE EFFECTS

Case Studies

Symptom profile and diagnostic utility of depersonalization–derealization disorder: A retrospective critical review from India

3.0

A retrospective 10-year study of 14 patients diagnosed with Depersonalization-derealization disorder (DPDR) in India, examining diagnosis frequency, symptoms, and treatment patterns at a tertiary psychiatry institute.

ssrissnrisantipsychoticslamotriginecarbamazepineopioid antagonists

Reddit Comments

Randommusings2013

1.0

## This is the only thing I've seen that confirmed this for me I am a new clinician and work in a high burn out field. Backstory: I've had bouts with mental illness in the past also with a previous traumatic brain injury in 2018. I've had 3 “breakdow...View more

VenlafaxineBupropionSnrisLamotrigineHydroxyzine

Reported Side Effects

Chest tightnessWithdrawal symptomsIbsIrritabilityAngerPanic attacksInsomnia

conversationqueen

1.0

## becoming hopeless guys this has been the roughest 4 months of my life. my dpdr is only getting worse, I cannot leave my house with out a panic attack & horrendous fight or flight, the thought of doing anything gives me anxiety, I have not felt lik...View more

SertralineSnris

Reported Side Effects

Weight gainFaintnessNo improvement